Thermoresponsive behavior of poly(DEGMA)-based copolymers. NMR and dynamic light scattering study of aqueous solutions

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F20%3A00520469" target="_blank" >RIV/61389013:_____/20:00520469 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0014305719322645?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0014305719322645?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.eurpolymj.2020.109488" target="_blank" >10.1016/j.eurpolymj.2020.109488</a>

Result language
angličtina
Original language name
Thermoresponsive behavior of poly(DEGMA)-based copolymers. NMR and dynamic light scattering study of aqueous solutions
Original language description
We studied temperature behavior of diblock copolymers of poly[2-(2-methoxyethoxy)ethyl methacrylate] (PDEGMA) with poly(N-(2-hydroxypropyl)methacrylamide and a statistical copolymer PDEGMA-co-N-propargylmethacrylamide in aqueous solutions. NMR spectra and dynamic light scattering showed that the copolymers exhibit a reversible phase transition which depends on the composition of the block copolymer and slightly on polymer concentration. In contrast to statistical copolymer, different behavior of proton groups in polymer backbone (and in the nearest side chain OCH2 group) on the one hand and in other side chain groups of the PDEGMA on the other hand was observed for diblock copolymers. Additionally, two types of water molecules were detected in solutions of the diblock copolymers above the phase transition –“free” with long and “bound” with short spin-spin relaxation times T2. NOESY spectra indicate that a core- to- shell morphology is unlikely in these block copolymers. This report emphasizes the importance of understanding of the self-association of copolymers in solution on the molecular level and provides important information for the design of “smart” thermoresponsive polymer-based drug delivery systems.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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