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Сolloidal probe based on iron(III)-doped calcium phytate nanoparticles for 31P NMR monitoring of bacterial siderophores

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F21%3A00542487" target="_blank" >RIV/61389013:_____/21:00542487 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S2215038221000674?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2215038221000674?via%3Dihub</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.colcom.2021.100427" target="_blank" >10.1016/j.colcom.2021.100427</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Сolloidal probe based on iron(III)-doped calcium phytate nanoparticles for 31P NMR monitoring of bacterial siderophores

  • Original language description

    A conceptually new class of probes was developed for detection of bacterial siderophores (BSPs), important determinants of virulence and pathogenicity, using 31P nuclear magnetic resonance (31P NMR). These probes are based on biodegradable nontoxic nanoparticles of calcium phytate (CaIP6), which possess measurable signal on 31P NMR spectra. The nanoparticles were doped with paramagnetic Fe3+ ions broadening the magnetic resonance signal of 31P. Therefore, the nanoparticles were not detectable by 31P NMR in the environment not containing BSPs, however, in the presence of BSPs, the Fe3+ ion is released from the nanoparticles, and the 31P NMR signal become detectable. In vitro demonstration of this Fe3+ release was performed with BSP deferoxamine (DFO), exhibiting a complete depletion of Fe3+ within 2 h for the nanoparticles containing 17.7 mol% Fe (III). The Fe3+ depletion was accompanied with a restoration of 31P NMR signal.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10404 - Polymer science

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Colloid and Interface Science Communications

  • ISSN

    2215-0382

  • e-ISSN

    2215-0382

  • Volume of the periodical

    42

  • Issue of the periodical within the volume

    May

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    6

  • Pages from-to

    100427

  • UT code for WoS article

    000658652600007

  • EID of the result in the Scopus database

    2-s2.0-85106305813