Role of dextran in stabilization of polypyrrole nanoparticles for photoacoustic imaging

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F21%3A00544172" target="_blank" >RIV/61389013:_____/21:00544172 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/21:10432593
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0014305721003682?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0014305721003682?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.eurpolymj.2021.110634" target="_blank" >10.1016/j.eurpolymj.2021.110634</a>

Result language
angličtina
Original language name
Role of dextran in stabilization of polypyrrole nanoparticles for photoacoustic imaging
Original language description
Polypyrrole with bioinert surface is a prospective contrast agent for photoacoustic imaging. Dextran (Dex) was successfully tested as a steric stabilizer of the dispersion polymerization producing stable polypyrrole nanoparticles (PPy-NPs). Polymerizations were mediated with three different oxidizers: iron (III) chloride, ammonium persulfate and cerium ammonium nitrate. The use of the Dex allowed good control of particle size within the range 60–200 nm through varying concentration of the Dex and polymerization temperature, with the exception of cerium mediated polymerizations, which produced 30 nm particles independently of the reaction conditions. Stabilization effect of the Dex resulted from a reversible adsorption of the Dex on the surface of nanoparticles. Spectral analysis confirmed the complete removal of the Dex from particle surfaces during washing procedure, which indicated no grafting of the Dex to PPy-NPs mediated with a radical process initiated with decay of persulfate or single electron oxidation of the Dex by cerium ammonium nitrate. Photoacoustic measurement proved detectable signals in near infrared regions.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

Project
<a href="/en/project/GA18-05200S" target="_blank" >GA18-05200S: Development of novel polymer contrast agents for photoacoustic in vivo imaging</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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