Glass ionomer cement modified by a imidazolium salt: adding antifungal properties to a biomaterial

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F21%3A00544228" target="_blank" >RIV/61389013:_____/21:00544228 - isvavai.cz</a>

Result on the web

<a href="https://link.springer.com/article/10.1007%2Fs42770-021-00511-5" target="_blank" >https://link.springer.com/article/10.1007%2Fs42770-021-00511-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s42770-021-00511-5" target="_blank" >10.1007/s42770-021-00511-5</a>

Result language

angličtina

Original language name

Glass ionomer cement modified by a imidazolium salt: adding antifungal properties to a biomaterial

Original language description

We present the structural modification of a commercially available glass ionomer cement by inserting the imidazolium salt 1-n-hexadecyl-3-methylimidazolium chloride (C16MImCl), composing a new biomaterial with antifungal biofilm activity. Test specimens were prepared using a commercial glass ionomer cement to which 10 ppm of cetylpyridinium chloride (reference ionic antifungal agent) or C16MImCl were added. The feasibility and hypoallergenicity of the new biomaterial were assessed by microhardness plastic deformation and chorioallantoic membrane assays. Colony counting and scanning electron microscopy were used to evaluate the modified specimens’ antibiofilm activity against three multidrug-resistant Candida species. The modified glass ionomer cement presented a strong antibiofilm activity against Candida spp., without losing its original micromechanical and hypoallergenic properties, rendering it a promising candidate for further application in dentistry.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10404 - Polymer science

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Brazilian Journal of Microbiology

ISSN

1517-8382

e-ISSN

1678-4405

Volume of the periodical

52

Issue of the periodical within the volume

3

Country of publishing house

BR - BRAZIL

Number of pages

6

Pages from-to

1347-1352

UT code for WoS article

000647499500001

EID of the result in the Scopus database

2-s2.0-85105654614