Cationic polymer-coated magnetic nanoparticles with antibacterial properties: synthesis and in vitro characterization

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F21%3A00545226" target="_blank" >RIV/61389013:_____/21:00545226 - isvavai.cz</a>
Alternative codes found
RIV/67985530:_____/21:00545226 RIV/00216208:11310/21:10442269
Result on the web
<a href="https://www.mdpi.com/2079-6382/10/9/1077" target="_blank" >https://www.mdpi.com/2079-6382/10/9/1077</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/antibiotics10091077" target="_blank" >10.3390/antibiotics10091077</a>

Result language
angličtina
Original language name
Cationic polymer-coated magnetic nanoparticles with antibacterial properties: synthesis and in vitro characterization
Original language description
Uniformly sized magnetite nanoparticles (Dn = 16 nm) were prepared by a thermal decomposition of Fe(III) oleate in octadec-1-ene and stabilized by oleic acid. The particles were coated with Sipomer PAM-200 containing both phosphate and methacrylic groups available for the attachment to the iron oxide and at the same time enabling (co)polymerization of 2-(dimethylamino)ethyl methacrylate and/or 2-tert-butylaminoethyl methacrylate at two molar ratios. The poly[2-(dimethylamino)ethyl methacrylate] (PDMAEMA) and poly[2-(dimethylamino)ethyl methacrylate-co-2-tert-butylaminoethyl methacrylate] [P(DMAEMA-TBAEMA)] polymers and the particles were characterized by 1H NMR spectroscopy, size-exclusion chromatography, transmission electron microscopy, dynamic light scattering, thermogravimetric analysis, magnetometry, and ATR FTIR and atomic absorption spectroscopy. The antimicrobial effect of cationic polymer-coated magnetite nanoparticles tested on both Escherichia coli and Staphylococcus aureus bacteria was found to be time- and dose-responsive. The P(DMAEMA-TBAEMA)-coated magnetite particles possessed superior biocidal properties compared to those of P(DMAEMA)-coated one.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science

Project
<a href="/en/project/GC20-02177J" target="_blank" >GC20-02177J: Antioxidant phenolic compound-modified magnetic nanoparticles for treatment of oxidative stress-related pathologies: Study of nano-biointerfaces</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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