Magnetic iron oxide particles for theranostics
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F22%3A00545664" target="_blank" >RIV/61389013:_____/22:00545664 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/chapter/10.1007%2F978-3-030-76235-3_4" target="_blank" >https://link.springer.com/chapter/10.1007%2F978-3-030-76235-3_4</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-030-76235-3_4" target="_blank" >10.1007/978-3-030-76235-3_4</a>
Alternative languages
Result language
angličtina
Original language name
Magnetic iron oxide particles for theranostics
Original language description
For many years, magnetic particles attracted a lot of interest in many fields, mainly including biomedicine. Recently, development of innovative strategies to tune the unique properties of magnetic nanoparticles for specific applications as theranostic agents has become one of the most challenging goals. This paper provides an overview of the synthesis, modification, and functionalization of magnetic nano- and microparticles. Special attention was paid to iron oxide composites used in cell separations and theranostics, such as anticancer drug delivery, diagnosis, and/or therapy of autoimmune and brain disorders. Last, but not the least, phenolic compound-modified magnetic particles were used as antioxidants or silver-containing carriers as antibacterial agents in in vitro and in vivo studies. Magnetic microparticles can be also incorporated in biosensors, exemplified by thionine-conjugated magnetic poly(carboxymethyl methacrylate-co-ethylene dimethacrylate) particles that showed higher enzymatic activity than nonmagnetic particles. Magnetic nano- and microparticles were characterized by a range of physicochemical methods, including transmission electron microscopy, dynamic light scattering, vibrating sample magnetometry, and Fourier-transform infrared spectroscopy, in terms of determination of particle morphology (size and its distribution), specific surface area, magnetic, and chemical properties. The chemical composition and crystallinity were confirmed by X-ray photoelectron spectroscopy. Moreover, the interactions between the magnetic particles and cells and/or other biological species were described.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
<a href="/en/project/GC20-02177J" target="_blank" >GC20-02177J: Antioxidant phenolic compound-modified magnetic nanoparticles for treatment of oxidative stress-related pathologies: Study of nano-biointerfaces</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Biomedical Nanomaterials
ISBN
978-3-030-76234-6
Number of pages of the result
21
Pages from-to
95-115
Number of pages of the book
330
Publisher name
Springer
Place of publication
Cham
UT code for WoS chapter
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