Structure-property relationships in PCL porous scaffolds obtained by means of the TIPS and TIPS-PL methods
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F23%3A00565879" target="_blank" >RIV/61389013:_____/23:00565879 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0142941822004275?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0142941822004275?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.polymertesting.2022.107906" target="_blank" >10.1016/j.polymertesting.2022.107906</a>
Alternative languages
Result language
angličtina
Original language name
Structure-property relationships in PCL porous scaffolds obtained by means of the TIPS and TIPS-PL methods
Original language description
This study aims at characterization of porous poly(ε-caprolactone) (PCL) scaffolds prepared by the methods of thermally induced phase separation (TIPS) and TIPS supported by particulate leaching (PL). Both techniques were combined with freeze-drying. Two PCL grades (with different average molecular weight characterized by MFR 6.1 and 1.2 g/10 min) were employed in the fabrication of scaffolds. Three types of salt (sodium chloride) particles were used in the TIPS-PL preparation of the PCL sample: (i) smaller particles (S) measuring 200–315 μm, (ii) larger particles (B) measuring 500–600 μm, and (iii) mixture of S and B particles (S/B = 1/1 wt/wt). The crystallization behavior of the PCL solutions and the thermal properties of scaffolds were investigated by polarized light microscopy (PLM) and differential scanning calorimetry (DSC), respectively. The structural changes of PCL were studied by attenuated total reflectance infrared spectroscopy (ATR-FTIR). The scaffold structure was visualized by means of scanning electron microscopy (SEM) and X-Ray micro-computed tomography (X-ray micro-CT). Furthermore, the density, porosity, water uptake, contact angle and compressive properties of scaffold were investigated. The molecular weight of PCL had an impact on the crystallization of the PCL solutions and thereby on the crystallinity of scaffolds and the morphology of pore walls formed during TIPS. Sodium chloride grains had an influence on the pore size and overall morphology of foam scaffolds prepared by TIPS-PL. The addition of NaCl decreased significantly the density and compressive properties and increased the porosity and water uptake of scaffolds.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10404 - Polymer science
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Polymer Testing
ISSN
0142-9418
e-ISSN
1873-2348
Volume of the periodical
118
Issue of the periodical within the volume
15 January
Country of publishing house
GB - UNITED KINGDOM
Number of pages
14
Pages from-to
107906
UT code for WoS article
000921400800001
EID of the result in the Scopus database
2-s2.0-85144429040