Raman spectroscopic investigation of polymer based magnetic multicomponent scaffolds
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F24%3A00588323" target="_blank" >RIV/61389013:_____/24:00588323 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S1386142524009661?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1386142524009661?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.saa.2024.124800" target="_blank" >10.1016/j.saa.2024.124800</a>
Alternative languages
Result language
angličtina
Original language name
Raman spectroscopic investigation of polymer based magnetic multicomponent scaffolds
Original language description
Scaffolds acting as an artificial matrix for cell proliferation are one of the bone tissue engineering approaches to the treatment of bone tissue defects. In the presented study, novel multicomponent scaffolds composed of a poly(ε-caprolactone) (PCL), phenolic compounds such as tannic (TA) and gallic acids (GA), and nanocomponents such as silica-coated magnetic iron oxide nanoparticles (MNPs-c) and functionalized multi-walled carbon nanotubes (CNTs) have been produced as candidates for such artificial substitutes. Well-developed interconnected porous structures were observed using scanning electron microscopy (SEM). Raman spectra showed that the highly crystalline nature of PCL was reduced by the addition of nanoadditives. In the case of scaffolds containing MNPs-c and TA, the formation of a Fe-TA complex was concluded because characteristic bands of chelation of the Fe3+ ion by phenolic catechol oxygen appeared. It was found that the necessary conditions for the crystallization of the PCL/MNPs-c/TA are for the catechol groups to be able to penetrate the porous silica shell of MNPs-c, as during experiment with MNPs-c and TA without polymer, no such complexation was observed. Moreover, the number of catechol groups, the spatial structure and molecular size of this phenolic compound are also crucial for complexation process because GA does not form complexes. Therefore, the PCL/CNTs/MNPs-c/TA scaffolds are interesting candidates to consider for their possible medical applications.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy
ISSN
1386-1425
e-ISSN
1873-3557
Volume of the periodical
322
Issue of the periodical within the volume
5 December
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
124800
UT code for WoS article
001273595400001
EID of the result in the Scopus database
2-s2.0-85198707691