Structure, network density and domain architecture of transition-metal (Cu2+, Fe3+) cross-linked alginates as seen by paramagnetic solid-state NMR spectroscopy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F25%3A00639379" target="_blank" >RIV/61389013:_____/25:00639379 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14160/25:00142068
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S014486172501152X?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S014486172501152X?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.carbpol.2025.124367" target="_blank" >10.1016/j.carbpol.2025.124367</a>
Alternative languages
Result language
angličtina
Original language name
Structure, network density and domain architecture of transition-metal (Cu2+, Fe3+) cross-linked alginates as seen by paramagnetic solid-state NMR spectroscopy
Original language description
Owing to the regenerative nature of metal-coordination bonds, transition metal-crosslinked alginates are of increasing technological relevance. However, due to their amorphous character and paramagnetic nature, their atomic-resolution structure, which is crucial for optimizing physicochemical properties, has long remained elusive. By employing very fast (VF) magic angle spinning (MAS) nuclear magnetic resonance (NMR) we overcame experimental challenges and obtained previously unreported data on the structure, network density, and domain architecture of alginates crosslinked by paramagnetic Cu2+ and Fe3+ ions, and modified by lactic acid - a pharmaceutically relevant ingredient that alters pH and crosslinking mechanism. We identified a high proportion of carboxyl units COOH coexisting with deprotonated carboxylate COO− groups, nanoscale acidic domains, and strongly hyperfine-coupled nuclei within the paramagnetic matrix, revealing the specific coordination geometry of the Cu2+ and Fe3+ ions utilizing hydroxyl groups. These results provide new insight into the structural complexity of amorphous paramagnetic biopolymers and demonstrate the analytical power of VF/MAS NMR in challenging environments. The present research thus aims to provide one of the first experimentally confirmed representations of the complex interactions in alginates crosslinked with paramagnetic transition metal ions. These findings have direct implications for the synthesis of novel functional materials based on carbohydrate polymers.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Carbohydrate Polymers
ISSN
0144-8617
e-ISSN
1879-1344
Volume of the periodical
370
Issue of the periodical within the volume
15 December
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
14
Pages from-to
124367
UT code for WoS article
001576870600004
EID of the result in the Scopus database
2-s2.0-105015960300