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Chloramines of amino acids as precursors of bactericidal activity in cell culture media DMEM and RPMI treated by RF-driven He/O<inf>2</inf> plasma jet

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389021%3A_____%2F23%3A00573458" target="_blank" >RIV/61389021:_____/23:00573458 - isvavai.cz</a>

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/10.1002/ppap.202300052" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/ppap.202300052</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/ppap.202300052" target="_blank" >10.1002/ppap.202300052</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Chloramines of amino acids as precursors of bactericidal activity in cell culture media DMEM and RPMI treated by RF-driven He/O<inf>2</inf> plasma jet

  • Original language description

    Antibacterial properties and chemical changes of two culture media, Dulbecco's Modified Eagle Medium (DMEM) and Roswell Park Memorial Institute (RPMI), treated by RF-driven He/O2 plasma jet, were studied using various chemical diagnostics and assessing Escherichia coli inactivation. The antibacterial effect increased with the plasma treatment time and was stronger in RPMI than in DMEM. Formation of organic mono- and dichloramines of amino acids in DMEM/RPMI by hypochlorite produced by the reaction of plasma-generated O atoms with Cl− ions present in culture media were the major causes of the biocidal activity. This behavior was attributed to the action of tertiary chemical products formed by the decay of organic dichloramines. The thiobarbituric acid assay revealed malondialdehyde formation from glucose oxidation as the major component of the media.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10404 - Polymer science

Result continuities

  • Project

    <a href="/en/project/GA19-25026S" target="_blank" >GA19-25026S: Characteristics of chemically reactive liquids produced by non-equilibrium plasma</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Plasma Processes and Polymers

  • ISSN

    1612-8850

  • e-ISSN

    1612-8869

  • Volume of the periodical

    20

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    14

  • Pages from-to

    e2300052

  • UT code for WoS article

    001003514200001

  • EID of the result in the Scopus database

    2-s2.0-85163111051