Inositol Trisphosphate-Induced Ca2+ Signaling Modulates Auxin Transport and PIN Polarity
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F11%3A00360769" target="_blank" >RIV/61389030:_____/11:00360769 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.devcel.2011.05.013" target="_blank" >http://dx.doi.org/10.1016/j.devcel.2011.05.013</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.devcel.2011.05.013" target="_blank" >10.1016/j.devcel.2011.05.013</a>
Alternative languages
Result language
angličtina
Original language name
Inositol Trisphosphate-Induced Ca2+ Signaling Modulates Auxin Transport and PIN Polarity
Original language description
Directional auxin flow within tissues depends on polar localization of PIN transporters. To explore regulation of PIN-mediated auxin transport, we screened for suppressors of PIN1 overexpression (supo) and identified an inositol polyphosphate 1-phosphatase mutant (supo1), with elevated inositol trisphosphate (InsP3) and cytosolic Ca2+ levels. Increases in InsP3 or Ca2+ levels also suppressed the PIN1 phenotypes and caused defects in basal PIN localization, auxin transport and auxin mediated development.Reductions in InsP3 levels and Ca2+ signaling antagonized the effects of the supo1 mutation and disrupted preferentially apical PIN localization. InsP3 and Ca2+ are evolutionarily conserved second messengers involved in various cellular functions, particularly stress responses. Our findings implicate them as modifiers of cell polarity and polar auxin transport, and highlight a potential integration point through which Ca2+ signaling-related stimuli could influence auxin-mediated develop
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Developmental Cell
ISSN
1534-5807
e-ISSN
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Volume of the periodical
20
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
855-866
UT code for WoS article
000291763500013
EID of the result in the Scopus database
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