Unlocking the Barley Genome by Chromosomal and Comparative Genomics

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F11%3A00365200" target="_blank" >RIV/61389030:_____/11:00365200 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1105/tpc.110.082537" target="_blank" >http://dx.doi.org/10.1105/tpc.110.082537</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1105/tpc.110.082537" target="_blank" >10.1105/tpc.110.082537</a>

Result language
angličtina
Original language name
Unlocking the Barley Genome by Chromosomal and Comparative Genomics
Original language description
We used a novel approach that incorporated chromosome sorting, next-generation sequencing, array hybridization, and systematic exploitation of conserved synteny with model grasses to assign -86% of the estimated -32,000 barley (Hordeum vulgare) genes toindividual chromosome arms. Using a series of bioinformatically constructed genome zippers that integrate gene indices of rice (Oryza sativa), sorghum (Sorghum bicolor), and Brachypodium distachyon in a conserved synteny model, we were able to assemble 21,766 barley genes in a putative linear order. We show that the barley (H) genome displays a mosaic of structural similarity to hexaploid bread wheat (Triticum aestivum) A, B, and D subgenomes and that orthologous genes in different grasses exhibit signatures of positive selection in different lineages. We present an ordered, information-rich scaffold of the barley genome that provides a valuable and robust framework for the development of novel strategies in cereal breeding.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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