A novel putative auxin carrier family regulates intracellular auxin homeostasis in plants

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F12%3A00380744" target="_blank" >RIV/61389030:_____/12:00380744 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15310/12:33142715

Result on the web

<a href="http://dx.doi.org/10.1038/nature11001" target="_blank" >http://dx.doi.org/10.1038/nature11001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/nature11001" target="_blank" >10.1038/nature11001</a>

Result language

angličtina

Original language name

A novel putative auxin carrier family regulates intracellular auxin homeostasis in plants

Original language description

The phytohormone auxin acts as a prominent signal, providing, by its local accumulation or depletion in selected cells, a spatial and temporal reference for changes in the developmental program. The distribution of auxin depends on both auxin metabolism(biosynthesis, conjugation and degradation) and cellular auxin transport. We identified in silico a novel putative auxin transport facilitator family, called PIN-LIKES (PILS). Here we illustrate that PILS proteins are required for auxin-dependent regulation of plant growth by determining the cellular sensitivity to auxin. PILS proteins regulate intracellular auxin accumulation at the endoplasmic reticulum and thus auxin availability for nuclear auxin signalling. PILS activity affects the level of endogenous auxin indole-3-acetic acid (IAA), presumably via intracellular accumulation and metabolism. Our findings reveal that the transport machinery to compartmentalize auxin within the cell is of an unexpected molecular complexity and demon

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nature

ISSN

0028-0836

e-ISSN

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Volume of the periodical

485

Issue of the periodical within the volume

7396

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

119-124

UT code for WoS article

000303451900046

EID of the result in the Scopus database

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