PLATELET AGGREGATION AND ANTI-INFLAMMATORY EFFECTS OF GARDEN PEA, DESI CHICKPEA AND KABULI CHICKPEA
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F12%3A00380748" target="_blank" >RIV/61389030:_____/12:00380748 - isvavai.cz</a>
Alternative codes found
RIV/60460709:41610/12:55850
Result on the web
<a href="http://home.ueb.cas.cz/publikace/2012_Haq_ACTA_POLONIAE_PHARMACEUTICA_707.pdf" target="_blank" >http://home.ueb.cas.cz/publikace/2012_Haq_ACTA_POLONIAE_PHARMACEUTICA_707.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
PLATELET AGGREGATION AND ANTI-INFLAMMATORY EFFECTS OF GARDEN PEA, DESI CHICKPEA AND KABULI CHICKPEA
Original language description
Inflammation is the natural body defense mechanism for the removal of injurious agents, necrosed cells and tissues from the body. This study was aimed to evaluate the anti-inflammatory and platelet aggregation effects of three medicinal plants of Pakistan. Methanolic extract of Garden pea inhibited arachidonic acid (AA)-induced platelet aggregation (IC50 = 35 ?g/mL) and platelet activating factor (PAF)-induced platelet aggregation (IC50 = 38 ?g/mL) in a dose dependent fashion. Methanolic extract of Desichickpea inhibited arachidonic acid (AA) induced platelet aggregation (IC50 value = AA = 46 ?g/mL) in dose dependent fashion while was found not active against PAF-induced platelet aggregation. Methanolic extract of Kabuli chickpea was found not activeagainst both arachidonic acid (AA)-induced platelet aggregation and PAF-induced platelet aggregation. The best potential to inhibit in vitro COX-2 activity showed garden pea (Pisum sativum; the synthesis of PGE2 reduced by 92% in comparis
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EF - Botany
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Acta Poloniae Pharmaceutica: drug research
ISSN
0001-6837
e-ISSN
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Volume of the periodical
69
Issue of the periodical within the volume
4
Country of publishing house
PL - POLAND
Number of pages
5
Pages from-to
707-711
UT code for WoS article
000307689100018
EID of the result in the Scopus database
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