The Leaf Reticulate Mutant dov1 Is Impaired in the First Step of Purine Metabolism

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F12%3A00388866" target="_blank" >RIV/61389030:_____/12:00388866 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15310/12:33142884

Result on the web

<a href="http://dx.doi.org/10.1093/mp/sss045" target="_blank" >http://dx.doi.org/10.1093/mp/sss045</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/mp/sss045" target="_blank" >10.1093/mp/sss045</a>

Result language

angličtina

Original language name

The Leaf Reticulate Mutant dov1 Is Impaired in the First Step of Purine Metabolism

Original language description

A series of reticulated Arabidopsis thaliana mutants were previously described. All mutants show a reticulate leaf pattern, namely green veins on a pale leaf lamina. They have an aberrant mesophyll structure but an intact layer of bundle sheath cells around the veins. Here, we unravel the function of the previously described reticulated EMS-mutant dov1 (differential development of vascular associated cells 1). By positional cloning, we identified the mutated gene, which encodes glutamine phosphoribosylpyrophosphate aminotransferase 2 (ATase2), an enzyme catalyzing the first step of purine nucleotide biosynthesis. dov1 is allelic to the previously characterized cia1-2 mutant that was isolated in a screen for mutants with impaired chloroplast protein import. We show that purine-derived total cytokinins are lowered in dov1 and crosses with phytohormone reporter lines revealed differential reporter activity patterns in dov1. Metabolite profiling unraveled that amino acids that are involve

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EC - Immunology

OECD FORD branch

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Project

<a href="/en/project/KAN200380801" target="_blank" >KAN200380801: Immunonanotechnologies for hormone diagnostic</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Molecular Plant

ISSN

1674-2052

e-ISSN

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Volume of the periodical

5

Issue of the periodical within the volume

6

Country of publishing house

GB - UNITED KINGDOM

Number of pages

15

Pages from-to

1227-1241

UT code for WoS article

000312573500010

EID of the result in the Scopus database

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