A convenient method for the preparation of 20-[O-18]-labeled ingenol

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F17%3A00476419" target="_blank" >RIV/61389030:_____/17:00476419 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15310/17:73584705

Result on the web

<a href="http://dx.doi.org/10.1016/j.tetlet.2017.02.078" target="_blank" >http://dx.doi.org/10.1016/j.tetlet.2017.02.078</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.tetlet.2017.02.078" target="_blank" >10.1016/j.tetlet.2017.02.078</a>

Result language

angličtina

Original language name

A convenient method for the preparation of 20-[O-18]-labeled ingenol

Original language description

A short and efficient protecting groupfree synthesis of isotopically labeled 20-[O-18]-ingenol has been developed. Based on a highly selective (only one out of four hydroxy groups) Mitsunobu reaction of ingenol with O-18(2)acetic acid and subsequent methanolysis, this route yielded the desired 20-[O-18]-ingenol in high yield and chemical and isotopic purity.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10401 - Organic chemistry

Project

<a href="/en/project/LO1204" target="_blank" >LO1204: Sustainable development of research in the Centre of the Region Haná</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Tetrahedron Letters

ISSN

0040-4039

e-ISSN

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Volume of the periodical

58

Issue of the periodical within the volume

14

Country of publishing house

GB - UNITED KINGDOM

Number of pages

4

Pages from-to

1421-1424

UT code for WoS article

000397699500014

EID of the result in the Scopus database

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