Synthesis of ergostane-type brassinosteroids with modifications in ring A

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F17%3A00482095" target="_blank" >RIV/61389030:_____/17:00482095 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15310/17:73584822
Result on the web
<a href="http://dx.doi.org/10.3762/bjoc.13.229" target="_blank" >http://dx.doi.org/10.3762/bjoc.13.229</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3762/bjoc.13.229" target="_blank" >10.3762/bjoc.13.229</a>

Result language
angličtina
Original language name
Synthesis of ergostane-type brassinosteroids with modifications in ring A
Original language description
Herein, we present a new strategy for the preparation of a broad range of brassinosteroid biosynthetic precursors/metabolites differing by the ring A fragment. The protocol is based on the use of readily available phytohormones of this class bearing a 2 alpha, 3 alpha-diol moiety (epibrassinolide or epicastasterone) as starting materials. The required functionalities (Delta(2)-, 2 alpha, 3 alpha- and 2 beta, 3 beta-epoxy-, 2 alpha, 3 beta-, 2 beta, 3 alpha-, and 2 beta, 3 beta-dihydroxy-, 3-keto-, 3a-and 3 beta-hydroxy-, 2 alpha-hydroxy-3-keto-) were synthesized from 2 alpha, 3 alpha-diols in a few simple steps (Corey-Winter reaction, epoxidation, oxidation, hydride reduction, etc.).
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10401 - Organic chemistry

Project
<a href="/en/project/LO1204" target="_blank" >LO1204: Sustainable development of research in the Centre of the Region Haná</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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