Ovarian Cancer: Differentially Expressed microRNAs in Tumor Tissue and Cell-Free Ascitic Fluid as Potential Novel Biomarkers
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F19%3A00510302" target="_blank" >RIV/61389030:_____/19:00510302 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/19:00112959 RIV/00216208:11110/19:10404254 RIV/65269705:_____/19:00071779 RIV/00064165:_____/19:10404254
Result on the web
<a href="http://dx.doi.org/10.1080/07357907.2019.1663208" target="_blank" >http://dx.doi.org/10.1080/07357907.2019.1663208</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/07357907.2019.1663208" target="_blank" >10.1080/07357907.2019.1663208</a>
Alternative languages
Result language
angličtina
Original language name
Ovarian Cancer: Differentially Expressed microRNAs in Tumor Tissue and Cell-Free Ascitic Fluid as Potential Novel Biomarkers
Original language description
Ovarian cancer is the deadliest gynecologic cancer. The large-scale microRNA (miRNA) expression profiling and individual miRNA validation was performed to find potential novel biomarkers for ovarian cancer. The most consistent overexpression of miRs-200b-3p, 135 b-5p and 182-5p was found in both ascitic fluid and tumors and suggests their potential as oncogenes. miR-451a was consistently underexpressed so may be a tumor suppressor. Results were inconsistent for miR-204-5p, which was overexpressed in ascitic fluid but underexpressed in tumor tissue. miR-203a-3p was generally overexpressed but this failed to be proved in independent sample set in tissue validation.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cancer Investigation
ISSN
0735-7907
e-ISSN
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Volume of the periodical
37
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
13
Pages from-to
440-452
UT code for WoS article
000486781600001
EID of the result in the Scopus database
2-s2.0-85073584075