Salicylic Acid Targets Protein Phosphatase 2A to Attenuate Growth in Plants

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F20%3A00522413" target="_blank" >RIV/61389030:_____/20:00522413 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/20:10408811 RIV/61989592:15310/20:73604898
Result on the web
<a href="https://doi.org/10.1016/j.cub.2019.11.058" target="_blank" >https://doi.org/10.1016/j.cub.2019.11.058</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.cub.2019.11.058" target="_blank" >10.1016/j.cub.2019.11.058</a>

Result language
angličtina
Original language name
Salicylic Acid Targets Protein Phosphatase 2A to Attenuate Growth in Plants
Original language description
Plants, like other multicellular organisms, survive through a delicate balance between growth and defense against pathogens. Salicylic acid (SA) is a major defense signal in plants, and the perception mechanism as well as downstream signaling activating the immune response are known. Here, we identify a parallel SA signaling that mediates growth attenuation. SA directly binds to A subunits of protein phosphatase 2A (PP2A), inhibiting activity of this complex. Among PP2A targets, the PIN2 auxin transporter is hyperphosphorylated in response to SA, leading to changed activity of this important growth regulator. Accordingly, auxin transport and auxin-mediated root development, including growth, gravitropic response, and lateral root organogenesis, are inhibited. This study reveals how SA, besides activating immunity, concomitantly attenuates growth through crosstalk with the auxin distribution network. Further analysis of this dual role of SA and characterization of additional SA-regulated PP2A targets will provide further insights into mechanisms maintaining a balance between growth and defense.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10609 - Biochemical research methods

Project
<a href="/en/project/EF16_019%2F0000738" target="_blank" >EF16_019/0000738: Centre for Experimental Plant Biology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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