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A review on the latest advances in extraction and analysis of artemisinin

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F20%3A00540409" target="_blank" >RIV/61389030:_____/20:00540409 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15310/20:73598553

  • Result on the web

    <a href="http://doi.org/10.1002/pca.2873" target="_blank" >http://doi.org/10.1002/pca.2873</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/pca.2873" target="_blank" >10.1002/pca.2873</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    A review on the latest advances in extraction and analysis of artemisinin

  • Original language description

    Introduction: Artemisinin (1), a well-known natural antimalarial drug, is a sesquiterpene lactone that contains a unique peroxide bridge. Since its discovery, the amount of research into the analysis of artemisinin has increased considerably, and it has been further intensified since the Noble Prize win by Tu Youyou in the year 2015 for the discovery of artemisinin. Objective: To review literature on the extraction and analysis of artemisinin, published during 2017–present, and to present an appraisal of those methods. Methodology: Extensive literature search was carried out which involved, but not limited to, the use of, various databases, like Web of Knowledge, PubMed and Google Scholar, and relevant published materials including published books. The keywords used, in various combinations, with artemisinin being present in all combinations, in the search were artemisinin, Artemisia annua, analysis, extraction, quantitative, qualitative and quality control. Results: During the period covered in this review, several methods of analysis of artemisinin have been reported, the most of which were liquid chromatography (LC)-based methods. However, the use of new methods like near-infrared analysis, fluorometirc analysis and molecular imprinting, and a significant increase in the use of computational tools have been observed. Mainly several methods involving supercritical fluid extraction and ultrasound-assisted extraction of artemisinin have dominated the extraction area. Conclusions: Newer analytical tools, as well as improved protocols for the known analytical tools, for qualitative and quantitative determination of artemisinin (1), have been made available by various researchers during the period covered by this review. Supercritical fluid extraction and ultrasound-assisted extraction are still the methods of choice for extraction of artemisinin.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

    <a href="/en/project/EF16_019%2F0000868" target="_blank" >EF16_019/0000868: Molecular, cellular and clinical approach to healthy ageing</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Phytochemical Analysis

  • ISSN

    0958-0344

  • e-ISSN

  • Volume of the periodical

    31

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    10

  • Pages from-to

    5-14

  • UT code for WoS article

    000612360400001

  • EID of the result in the Scopus database

    2-s2.0-85070094493