Insights into the role of transcriptional gene silencing in response to herbicide‐treatments in arabidopsis thaliana
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F21%3A00545881" target="_blank" >RIV/61389030:_____/21:00545881 - isvavai.cz</a>
Result on the web
<a href="http://doi.org/10.3390/ijms22073314" target="_blank" >http://doi.org/10.3390/ijms22073314</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms22073314" target="_blank" >10.3390/ijms22073314</a>
Alternative languages
Result language
angličtina
Original language name
Insights into the role of transcriptional gene silencing in response to herbicide‐treatments in arabidopsis thaliana
Original language description
Herbicide resistance is broadly recognized as the adaptive evolution of weed populations to the intense selection pressure imposed by the herbicide applications. Here, we tested whether transcriptional gene silencing (TGS) and RNA‐directed DNA Methylation (RdDM) pathways mod-ulate resistance to commonly applied herbicides. Using Arabidopsis thaliana wild‐type plants exposed to sublethal doses of glyphosate, imazethapyr, and 2,4‐D, we found a partial loss of TGS and increased susceptibility to herbicides in six out of 11 tested TGS/RdDM mutants. Mutation in RE‐ PRESSOR OF SILENCING 1 (ROS1), that plays an important role in DNA demethylation, leading to strongly increased susceptibility to all applied herbicides, and imazethapyr in particular. Tran-scriptomic analysis of the imazethapyr‐treated wild type and ros1 plants revealed a relation of the herbicide upregulated genes to chemical stimulus, secondary metabolism, stress condition, flavonoid biosynthesis, and epigenetic processes. Hypersensitivity to imazethapyr of the flavonoid bio-synthesis component TRANSPARENT TESTA 4 (TT4) mutant plants strongly suggests that ROS1‐ dependent accumulation of flavonoids is an important mechanism for herbicide stress response in A. thaliana. In summary, our study shows that herbicide treatment affects transcriptional gene silencing pathways and that misregulation of these pathways makes Arabidopsis plants more sensitive to herbicide treatment.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
<a href="/en/project/EF16_019%2F0000827" target="_blank" >EF16_019/0000827: Plants as a tool for sustainable global development</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Molecular Sciences
ISSN
1422-0067
e-ISSN
1422-0067
Volume of the periodical
22
Issue of the periodical within the volume
7
Country of publishing house
CH - SWITZERLAND
Number of pages
20
Pages from-to
3314
UT code for WoS article
000638669600001
EID of the result in the Scopus database
2-s2.0-85102920035