The effect of the manure from sheep treated with anthelmintics on clover (Trifolium pratense)

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F21%3A00551726" target="_blank" >RIV/61389030:_____/21:00551726 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11160/21:10434145

Result on the web

<a href="http://doi.org/10.3390/agronomy11091892" target="_blank" >http://doi.org/10.3390/agronomy11091892</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/agronomy11091892" target="_blank" >10.3390/agronomy11091892</a>

Result language

angličtina

Original language name

The effect of the manure from sheep treated with anthelmintics on clover (Trifolium pratense)

Original language description

The anthelmintics (regularly administered to livestock to control the infections caused by parasitic worms) and their metabolites formed in treated animals are excreted to the environment. This contamination might have a negative influence on non-target organisms including plants. Our previous studies described the uptake, metabolism, and effects of anthelmintics in plants using in vitro models exposed to anthelmintic drugs in solutions. The present study was performed in clover grown in soil fertilized with manure from sheep treated with the recommended dose of albendazole (ABZ), ivermectin (IVM), or monepantel (MOP). The uptake and metabolism of drugs in clover were monitored for six weeks using UHPLC-MS/MS, and several stress markers (proline accumulation, lipid peroxidation, and antioxidant enzymes activities) were evaluated. The results showed that ABZ and MOP were absorbed, metabolized, and translocated to leaves, while IVM was detected only in the roots. No or minimal drug-response was observed in monitored stress markers, and only a temporary increase of several antioxidative enzymes activities was observed. Overall, manure from sheep treated with anthelmintics does not evoke chronic stress in clover, but it can cause the entry of anthelmintics in other organisms and the food-chain.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30104 - Pharmacology and pharmacy

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Agronomy

ISSN

2073-4395

e-ISSN

2073-4395

Volume of the periodical

11

Issue of the periodical within the volume

9

Country of publishing house

CH - SWITZERLAND

Number of pages

14

Pages from-to

1892

UT code for WoS article

000699245100001

EID of the result in the Scopus database

2-s2.0-85116638432