Triterpenoid Building Blocks for Functional Nanoscale Assemblies: A Review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F22%3A00564512" target="_blank" >RIV/61389030:_____/22:00564512 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22330/22:43924766
Result on the web
<a href="https://doi.org/10.1021/acsanm.2c03304" target="_blank" >https://doi.org/10.1021/acsanm.2c03304</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acsanm.2c03304" target="_blank" >10.1021/acsanm.2c03304</a>
Alternative languages
Result language
angličtina
Original language name
Triterpenoid Building Blocks for Functional Nanoscale Assemblies: A Review
Original language description
Naturally abundant, renewable, and sustainable plant triterpenoids have gained considerable attention in biological application, including antitumor activities. However, due to their lipophilic nature, natural triterpenoids display limited solubility in aqueous media. Notably, the rigid backbone and the presence of functional groups also offer the possibilities toward a strategic design of a class of conformationally rigid amphiphiles. Such derivatives may improve their bioavailability, and they display unique self-assembly properties relevant for soft functional materials. In recent years, a formation of nano-assemblies has been studied with plant triterpenoids and their semisynthetic derivatives to investigate ways of their applications in materials science. For example, naturally amphiphilic glycyrrhizic acid has been shown to form hydrogels. Similarly, other natural triterpenoid-based phosphates or heterocyclic-based quaternary conjugates have also been studied for supramolecular gelation. Triterpenoid-based supramolecular gels are important types of soft materials, displaying rapid self-healing, thixotropic behaviors, aging-induced transition, and self-assembly-induced anticancer and antimicrobial properties. In this review, we will provide a summary of (i) unique structural and functional properties of natural triterpenoids, (ii) self-assembly and gelation properties of natural triterpenoids, (iii) gelation properties of rationally designed triterpenoid derivatives, (iv) structural transition in aqueous media, and (v) their biological effects.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10401 - Organic chemistry
Result continuities
Project
<a href="/en/project/FV10599" target="_blank" >FV10599: Gels based on plant triterpenoid acids</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ACS Applied Nano Materials
ISSN
2574-0970
e-ISSN
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Volume of the periodical
5
Issue of the periodical within the volume
11
Country of publishing house
US - UNITED STATES
Number of pages
14
Pages from-to
16264-16277
UT code for WoS article
000882971600001
EID of the result in the Scopus database
2-s2.0-85141640278