The wheat stem rust resistance gene Sr43 encodes an unusual protein kinase
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F23%3A00575378" target="_blank" >RIV/61389030:_____/23:00575378 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1038/s41588-023-01402-1" target="_blank" >https://doi.org/10.1038/s41588-023-01402-1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41588-023-01402-1" target="_blank" >10.1038/s41588-023-01402-1</a>
Alternative languages
Result language
angličtina
Original language name
The wheat stem rust resistance gene Sr43 encodes an unusual protein kinase
Original language description
To safeguard bread wheat against pests and diseases, breeders have introduced over 200 resistance genes into its genome, thus nearly doubling the number of designated resistance genes in the wheat gene pool1. Isolating these genes facilitates their fast-tracking in breeding programs and incorporation into polygene stacks for more durable resistance. We cloned the stem rust resistance gene Sr43, which was crossed into bread wheat from the wild grass Thinopyrum elongatum 2,3. Sr43 encodes an active protein kinase fused to two domains of unknown function. The gene, which is unique to the Triticeae, appears to have arisen through a gene fusion event 6.7 to 11.6 million years ago. Transgenic expression of Sr43 in wheat conferred high levels of resistance to a wide range of isolates of the pathogen causing stem rust, highlighting the potential value of Sr43 in resistance breeding and engineering.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
<a href="/en/project/EF16_019%2F0000827" target="_blank" >EF16_019/0000827: Plants as a tool for sustainable global development</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nature Genetics
ISSN
1061-4036
e-ISSN
1546-1718
Volume of the periodical
55
Issue of the periodical within the volume
6
Country of publishing house
DE - GERMANY
Number of pages
6
Pages from-to
921-926
UT code for WoS article
000993686600002
EID of the result in the Scopus database
2-s2.0-85160030197