Alkaloid-rich extract of jujube seed regenerate the antiproliferative effect of paclitaxel on paclitaxel-resistant MDA-MB-231 breast cancer cell line in 2D and 3D cultures

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F24%3A00600984" target="_blank" >RIV/61389030:_____/24:00600984 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.jafr.2024.101438" target="_blank" >https://doi.org/10.1016/j.jafr.2024.101438</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jafr.2024.101438" target="_blank" >10.1016/j.jafr.2024.101438</a>

Result language
angličtina
Original language name
Alkaloid-rich extract of jujube seed regenerate the antiproliferative effect of paclitaxel on paclitaxel-resistant MDA-MB-231 breast cancer cell line in 2D and 3D cultures
Original language description
Cancer is the second leading cause of death globally, and among all types of cancer, triple-negative breast cancer (TNBC) has one of the worst prognoses. The repeated use of chemotherapeutic drugs often leads to drug resistance, complicating treatment outcomes. This study aimed to investigate the effect of jujube alkaloid-rich extract on drug sensitivity and its antitumor effects on paclitaxel-resistant MDA-MB-231 cells in vitro.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology

Project
<a href="/en/project/GA23-05389S" target="_blank" >GA23-05389S: Novel CB2 and BChE modulators against Parkinson's disease and related pathologies</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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