Progress in the analysis of phytocannabinoids by HPLC and UPLC (or UHPLC) during 2020-2023
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F24%3A00602119" target="_blank" >RIV/61389030:_____/24:00602119 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15310/24:73628608
Result on the web
<a href="https://doi.org/10.1002/pca.3374" target="_blank" >https://doi.org/10.1002/pca.3374</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/pca.3374" target="_blank" >10.1002/pca.3374</a>
Alternative languages
Result language
angličtina
Original language name
Progress in the analysis of phytocannabinoids by HPLC and UPLC (or UHPLC) during 2020-2023
Original language description
Organic molecules that bind to cannabinoid receptors are known as cannabinoids. These molecules possess pharmacological properties similar to those produced by Cannabis sativa L. High-performance liquid chromatography (HPLC) and ultra-performance liquid chromatography (UPLC, also known as ultra-high-performance liquid chromatography, UHPLC) have become the most widely used analytical tools for detection and quantification of phytocannabinoids in various matrices. HPLC and UPLC (or UHPLC) are usually coupled to an ultraviolet (UV), photodiode array (PDA), or mass spectrometric (MS) detector. ObjectiveTo critically appraise the literature on the application of HPLC and UPLC (or UHPLC) methods for the analysis of phytocannabinoids published from January 2020 to December 2023. MethodologyAn extensive literature search was conducted using Web of Science, PubMed, and Google Scholar and published materials including relevant books. In various combinations, using cannabinoid in all combinations, cannabis, hemp, hashish, C. sativa, marijuana, analysis, HPLC, UHPLC, UPLC, and quantitative, qualitative, and quality control were used as the keywords for the literature search. ResultsSeveral HPLC- and UPLC (or UHPLC)-based methods for the analysis of phytocannabinoids were reported. While simple HPLC-UV or HPLC-PDA-based methods were common, the use of HPLC-MS, HPLC-MS/MS, UPLC (or UHPLC)-PDA, UPLC (or UHPLC)-MS, and UPLC (or UHPLC)-MS/MS was also reported. Applications of mathematical and computational models for optimization of protocols were noted. Pre-analyses included various environmentally friendly extraction protocols. ConclusionDuring the last 4 years, HPLC and UPLC (or UHPLC) remained the main analytical tools for phytocannabinoid analysis in different matrices.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Phytochemical Analysis
ISSN
0958-0344
e-ISSN
1099-1565
Volume of the periodical
35
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
63
Pages from-to
927-989
UT code for WoS article
001238956600001
EID of the result in the Scopus database
2-s2.0-85195187975