Polarity-guided uneven mitotic divisions control brassinosteroid activity in proliferating plant root cells
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F25%3A00619887" target="_blank" >RIV/61389030:_____/25:00619887 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/25:10509107
Result on the web
<a href="https://doi.org/10.1016/j.cell.2025.02.011" target="_blank" >https://doi.org/10.1016/j.cell.2025.02.011</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.cell.2025.02.011" target="_blank" >10.1016/j.cell.2025.02.011</a>
Alternative languages
Result language
angličtina
Original language name
Polarity-guided uneven mitotic divisions control brassinosteroid activity in proliferating plant root cells
Original language description
Brassinosteroid hormones are positive regulators of plant organ growth, yet their function in proliferating tissues remains unclear. Here, through integrating single-cell RNA sequencing with long-term live-cell imaging of the Arabidopsis root, we reveal that brassinosteroid activity fluctuates throughout the cell cycle, decreasing during mitotic divisions and increasing during the G1 phase. The post-mitotic recovery of brassinosteroid activity is driven by the intrinsic polarity of the mother cell, resulting in one daughter cell with enhanced brassinosteroid signaling, while the other supports brassinosteroid biosynthesis. The coexistence of these distinct daughter cell states during the G1 phase circumvents a negative feedback loop to facilitate brassinosteroid production while signaling increases. Our findings uncover polarity-guided, uneven mitotic divisions in the meristem, which control brassinosteroid hormone activity to ensure optimal root growth.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10601 - Cell biology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cell
ISSN
0092-8674
e-ISSN
1097-4172
Volume of the periodical
188
Issue of the periodical within the volume
8
Country of publishing house
GB - UNITED KINGDOM
Number of pages
18
Pages from-to
2063-2080
UT code for WoS article
001476122000001
EID of the result in the Scopus database
2-s2.0-86000636557