Hypocholesterolaemia on the medical intensive care unit: The process of cholesterol synthesis rption is altered in the acute phase of disease

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F09%3AA1000VSV" target="_blank" >RIV/61988987:17110/09:A1000VSV - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Hypocholesterolaemia on the medical intensive care unit: The process of cholesterol synthesis rption is altered in the acute phase of disease

Original language description

The aim of this study is to describe the changes of cholesterol metabolism in patients with acute medical disease. The study included 60 patients with acute medical disease solely on artificial nutrition. Plasma concentrations of total cholesterol, HDL and LDL cholesterol were measured on days 0,3 and 7. Lathosterol, squalene, sitosterol and campesterol concentrations were determined on days 3 and 7. The metabolic parameters were compared with a control group.Results: We detected a statistically significant decrease in total chol.concentration, and lower plasma levels of LDL and HDL chol. A statistically significant decrease in lathosterol and campesterol plasma levels was detected. Sitosterol concentrations were lower but not significantly. The concentration of squalene was noted to be higher than in the control group.Concl.Our results show abnormalities in the chol.metabolism, including both arms of the cholesterol acquisition process, in patients with acute medical disease.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FE - Other fields of internal medicine

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Anest Int Med

ISSN

1214-2158

e-ISSN

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Volume of the periodical

20

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

6

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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