Development of a treatment of pregnant women suffering from epilepsy in the region of Ostrava between the years 1991 and 2006

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F10%3AA1101094" target="_blank" >RIV/61988987:17110/10:A1101094 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Development of a treatment of pregnant women suffering from epilepsy in the region of Ostrava between the years 1991 and 2006

Original language description

The paper discusses long-term trends in the utilization of antiepileptic drugs during pregnancy and reports an analysis of their concentations at delivery. The reguest forms for routine therapeutic drug monitoring and concentrations of antiepileptic drugs at delivery collected between the years 1991-2006 were used as the data source. Monotherapy versus polytherapy, the utilization of individual antiepileptic drugs and combinations, and concentations were monitored in a group of 235 pregnancies within three 5-year periods. Monotherapy was used in 61 % in the years 1991-1995, in 68% in the years 1996-2000, and in 75 % in the years 2001-2006. During the 1 st period, the most frequently prescribed agents were phenytoin, carbamazepine and primidone, duringthe 2 nd period, carbamazepine, phenytoin, and valproic acid, and during the 3 rd period, carbamazepine, lamotrigine, and valproic acid. Concentations were mostly under the therapeutics range with an exception ofcarbamazepine and primidon

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Česká a slovenská farmacie

ISSN

1210-7816

e-ISSN

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Volume of the periodical

4

Issue of the periodical within the volume

59

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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