Are changes in heart rate variability in middle-aged and older people normative or due to pathological conditions? Findings from a large population-based longitudinal cohort study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F16%3AA1701F9Z" target="_blank" >RIV/61988987:17110/16:A1701F9Z - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Are changes in heart rate variability in middle-aged and older people normative or due to pathological conditions? Findings from a large population-based longitudinal cohort study
Original language description
No study to date has investigated longitudinal trajectories of cardiac autonomic modulation changes with aging; therefore, we lack evidence showing whether these changes occur naturally or are secondary to disease or medication use. This study tested whether heart rate variability (HRV) trajectories from middle to older age are largely normative or caused by pathological changes with aging in a large prospective cohort. We further assessed whether HRV changes were modified by socioeconomic status, ethnicity, or habitual physical activity. This study involved 3176 men and 1238 women initially aged 44 to 69 years (1997-1999) from the UK Whitehall II population?based cohort. We evaluated time? and frequency?domain HRV measures of short?term recordings at 3 time points over a 10?year period. Random mixed models with time?varying covariates were applied. Cross?sectionally, HRV measures were lower for men than for women, for participants with cardiometabolic conditions, and for participants reporting
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FN - Epidemiology, infection diseases and clinical immunology
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of American Heart Association
ISSN
2047-9980
e-ISSN
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Volume of the periodical
feb 2016
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
13
Pages from-to
1-13
UT code for WoS article
000378131100024
EID of the result in the Scopus database
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