Carbon dioxide insufflation during colonoscopy in inflammatory bowel disease patients: A double-blind, randomized, single-center trial

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F17%3AA1701M1N" target="_blank" >RIV/61988987:17110/17:A1701M1N - isvavai.cz</a>

Alternative codes found

RIV/00023761:_____/17:N0000003

Result on the web

<a href="https://www.ncbi.nlm.nih.gov/pubmed/27845950" target="_blank" >https://www.ncbi.nlm.nih.gov/pubmed/27845950</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/MEG.0000000000000791" target="_blank" >10.1097/MEG.0000000000000791</a>

Result language

angličtina

Original language name

Carbon dioxide insufflation during colonoscopy in inflammatory bowel disease patients: A double-blind, randomized, single-center trial

Original language description

Objective Bowel distension by insufflated air causes abdominal discomfort after colonoscopy. Carbon dioxide (CO 2) instead of air insufflation during colonoscopy can reduce postprocedural discomfort in diagnostic and screening cases. Discomfort after colonoscopy and CO 2 insufflation have never been studied in inflammatory bowel disease (IBD) patients, characterized by younger age, structural changes of the colon, and need for repeated and frequently uncomfortable colonoscopies. Our trial was designed to evaluate postprocedural discomfort associated with CO 2 compared with air insufflation in unsedated or minimally sedated patients with known IBD. Methods In a double-blind, randomized, single-center study, 64 patients were randomized to either CO 2 insufflation (CO 2) or air insufflation colonoscopy (Air). Abdominal pain, bloating, and flatulence scores during 24 h after colonoscopy were recorded using a continuous scale of 0-10 (0=none, 10=maximum discomfort). The primary endpoint used for power calculation was bloating score at 1 h after colonoscopy. Results Pain, bloating, and flatulence scores at end, 1, and 3 h after colonoscopy were significantly lower in CO 2 than in Air arm (P<0.001). Scores at 6, 12, and 24 h were comparable. Procedural parameters such as cecal and terminal ileum intubation rate, intubation and total time, pain during insertion, need for repositioning, and abdominal compression were not different between arms. No complications were recorded in the study. Conclusion Compared with air, CO 2 insufflation significantly reduces abdominal pain, bloating, and flatulence scores during at least 3 h after colonoscopy in IBD patients, achieving comparable intraprocedural outcomes. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30219 - Gastroenterology and hepatology

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

EUR J GASTROEN HEPAT

ISSN

0954-691X

e-ISSN

—

Volume of the periodical

29

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

5

Pages from-to

355-359

UT code for WoS article

000393773100018

EID of the result in the Scopus database

2-s2.0-84995466957