The role of narrow-band imaging (NBI) endoscopy in optical biopsy of vocal cord leukoplakia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F17%3AA1801S48" target="_blank" >RIV/61988987:17110/17:A1801S48 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/17:10367478 RIV/00179906:_____/17:10367478 RIV/00843989:_____/17:E0105902
Result on the web
<a href="http://dx.doi.org/10.1007/s00405-016-4244-6" target="_blank" >http://dx.doi.org/10.1007/s00405-016-4244-6</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00405-016-4244-6" target="_blank" >10.1007/s00405-016-4244-6</a>
Alternative languages
Result language
angličtina
Original language name
The role of narrow-band imaging (NBI) endoscopy in optical biopsy of vocal cord leukoplakia
Original language description
The aim of this study was to investigate whether observing microvascular changes by narrow-band imaging (NBI) endoscopy in the area surrounding leukoplakia is sufficient for discriminating between benign and malignant patterns of vocal cord leukoplakia. A total of 282 patients were investigated using white-light high-definition TV laryngoscopy and NBI endoscopy from 6/2013 to 8/2015, and 63 patients with a primary case of laryngeal leukoplakia were enrolled. Patients were divided into two groups based on leukoplakia with surrounding malignant intraepithelial papillary capillary loops (group I; 26/63) and leukoplakia with a surrounding benign vascular network (group II; 37/63), both by NBI endoscopy. All 63 patients were evaluated by blinded histological examination, and results were compared with NBI optical biopsy. Carcinoma in situ or invasive squamous cell carcinoma was confirmed in 22/26 cases (84.6 %) in group I. Hyperkeratosis or low-grade dysplasia was confirmed histologically in 31/37 (83.8 %) and squamous cell carcinoma in 2/37 (5.4 %) cases in group II. Accordance of NBI endoscopy and histopathological features of vocal cord leukoplakia lesions was statistically significant (kappa index 0.77, p < 0.001), with a sensitivity of 88.0 % (95 % CI 67.8-97.5 %) and specificity of 89.5 % (95 % CI 71.2-97.1 %). NBI is convenient for improving evaluation of laryngeal leukoplakias based on optic prehistological diagnosis. The close accordance between NBI features and histological results suggests that a negative NBI endoscopy may be an indication for long-term endoscopy follow-up without histological evaluation.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30206 - Otorhinolaryngology
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
ISSN
0937-4477
e-ISSN
1434-4726
Volume of the periodical
274
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
355-359
UT code for WoS article
000393599900044
EID of the result in the Scopus database
2-s2.0-84981521022