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Role of confocal laser endomicroscopy in patients with early esophageal neoplasia

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F18%3AA1901VW5" target="_blank" >RIV/61988987:17110/18:A1901VW5 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/18:10381812 RIV/00023001:_____/18:00077431

  • Result on the web

    <a href="http://dx.doi.org/10.23736/S0026-4733.18.07795-7" target="_blank" >http://dx.doi.org/10.23736/S0026-4733.18.07795-7</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.23736/S0026-4733.18.07795-7" target="_blank" >10.23736/S0026-4733.18.07795-7</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Role of confocal laser endomicroscopy in patients with early esophageal neoplasia

  • Original language description

    Probe-based confocal laser endomicroscopy (pCLE) enables real-time histopathological assessment during endoscopic procedures to evaluate epithelial and subepithelial structures with a 1000x magnification. It may be used in various localizations not only in the digestive tract, but its role in clinical practice is still a matter of discussion. The main advantages of pCLE compared to standard biopsies may be: 1) real-time diagnosis; 2) which may be done by the endoscopist; and 3) a larger evaluated area compared to standard biopsies. In theory, pCLE has the potential to eliminate the need for biopsy. However, pCLE cannot replace standard biopsies at this time, among others, standard forceps biopsies are presently more cost-effective. pCLE may be used to enhance the diagnostic arsenal and improve mucosal visualization and evaluation in patients with Barrett's esophagus (BE), with visible esophageal lesions and in patients undergoing surveillance endoscopy after endoscopic treatment of BE related neoplasia. pCLE requires sufficient training and use of validated classifications systems. At present, the majority of endoscopic centers do not use pCLE routinely and no guidelines recommend its routine use for patients with different esophageal diseases, although pCLE is (in selected indications) reimbursed in some countries. This article describes the principle and performance of pCLE and reviews its use in patients with BE and early esophageal neoplasia.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30212 - Surgery

Result continuities

  • Project

    <a href="/en/project/NV16-27648A" target="_blank" >NV16-27648A: Probe-based confocal laser endomicroscopy in accurate histopathologic diagnosis of neoplastic gastrointestinal lesions</a><br>

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    MINERVA CHIRURGICA

  • ISSN

    0026-4733

  • e-ISSN

    1827-1626

  • Volume of the periodical

    73

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    IT - ITALY

  • Number of pages

    11

  • Pages from-to

    417-427

  • UT code for WoS article

    000445223700008

  • EID of the result in the Scopus database

    2-s2.0-85051108847