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Prehospital stroke scale (FAST PLUS Test) predicts patients with intracranial large vessel occlusion

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F18%3AA1901Z6A" target="_blank" >RIV/61988987:17110/18:A1901Z6A - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/18:00104208 RIV/00843989:_____/18:E0107240 RIV/00159816:_____/18:00069259

  • Result on the web

    <a href="http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=AuthorFinder&qid=23&SID=D13SSqgZZvWdLAysw83&page=1&doc=10" target="_blank" >http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=AuthorFinder&qid=23&SID=D13SSqgZZvWdLAysw83&page=1&doc=10</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/brb3.1087" target="_blank" >10.1002/brb3.1087</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Prehospital stroke scale (FAST PLUS Test) predicts patients with intracranial large vessel occlusion

  • Original language description

    Background and Purpose: Mechanical thrombectomy (MT) is indicated for the treatment of large vessel occlusion (LVO) stroke. MT should be provided as quickly as possible; therefore, a test identifying suspected LVO in the prehospitalization stage is needed to ensure direct transport to a comprehensive stroke center (CSC). We assume that patients with clinically severe hemiparesis have a high probability of LVO stroke. We modified the FAST test into the FAST PLUS test: The first part is the FAST test and the second part evaluates the presence of severe arm or leg motor deficit. This prospective multicenter study evaluates the specificity and sensitivity of the FAST PLUS test in detecting LVO stroke. Methods: Paramedics were trained through e-learning to conduct the FAST PLUS test. All prehospital suspected stroke patients who were administered the FAST PLUS test were included. Demographics, National Institutes of Health Stroke Scale (NIHSS) score, brain computed tomography (CT), and CT angiography (CTA) were recorded. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and receiver operating curve (ROC) area for LVO were calculated. Results: The study included 435 patients. LVO were found in 124 patients (28%). Sensitivity was 93%, specificity was 47%, PPV was 41%, NPV was 94%, and ROC area for ICA/MCA occlusion was 0.65. Intracerebral hemorrhage (ICH) was identified in 48 patients (11%). Conclusion: We found that the FAST PLUS test had a high sensitivity for LVO stroke. Of the 435 patients, 41% were all directly transported to a CSC based on positive FAST PLUS test scores and were potential candidates for MT.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30103 - Neurosciences (including psychophysiology)

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Brain and Behavior

  • ISSN

    2162-3279

  • e-ISSN

  • Volume of the periodical

    8

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    1-7

  • UT code for WoS article

    000445850000019

  • EID of the result in the Scopus database