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24-Hour Alberta Stroke Program Early CT Score Assessment in Post-Stroke Spasticity Development in Patients with a First Documented Anterior Circulation Ischemic Stroke

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F18%3AA20020Q9" target="_blank" >RIV/61988987:17110/18:A20020Q9 - isvavai.cz</a>

  • Alternative codes found

    RIV/00159816:_____/18:00068028 RIV/00216224:14110/18:00102114

  • Result on the web

    <a href="https://reader.elsevier.com/reader/sd/pii/S1052305717304548?token=B88D5E67FD9EDF05F973D3F1182737660A677FA23CC05A4DE240D74A09A084E2AD9BE76612552ADD09A9E70EC7C9E60C" target="_blank" >https://reader.elsevier.com/reader/sd/pii/S1052305717304548?token=B88D5E67FD9EDF05F973D3F1182737660A677FA23CC05A4DE240D74A09A084E2AD9BE76612552ADD09A9E70EC7C9E60C</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.08.033" target="_blank" >10.1016/j.jstrokecerebrovasdis.2017.08.033</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    24-Hour Alberta Stroke Program Early CT Score Assessment in Post-Stroke Spasticity Development in Patients with a First Documented Anterior Circulation Ischemic Stroke

  • Original language description

    Background: Neuroanatomic substrates responsible for development of post-stroke spasticity are still poorly understood. The study is focused on identification of brain regions within the territory of the middle cerebral artery associated with spasticity development. Methods: This is a single-center prospective cohort study of first documented anterior circulation ischemic strokes with a neurologic deficit lasting >7 days (from March 2014 to September 2016, all patients are involved in a registry). Ischemic cerebral lesions within the territory of middle cerebral artery were evaluated using the Alberta Stroke Program Early CT Score (ASPECTS) on control 24-hour computed tomography or magnetic resonance imaging. Spasticity was assessed with modified Ashworth scale. Results: Seventy-six patients (mean age 72 years, 45% females; 30% treated with IV tissue plasminogen activator, 6.5% mechanical thrombectomy) fulfilled the study inclusion criteria. Forty-nine (64%) developed early elbow or wrist flexor spasticity defined as modified Ashworth scale >1 (at day 7-10), in 44 (58%) the spasticity remained present at 6 months. There were no differences between the patients who developed spasticity and those who did not when comparing admission stroke severity (National Institutes of Health Stroke Scale 5 [interquartile range {IQR} 4-8] versus 6 [IQR 4-10]) and vascular risk factors (hypertension, diabetes mellitus, dyslipidemia, atrial fibrillation, coronary artery disease). Nor was there a difference in 24-hour ASPECTS score (9 DQR 8-10] versus 9 DQR 7-10]). No differences were found between the groups with and without the early upper limb flexor spasticity of particular regions (M1, M2, M3, M4, M5, M6, lentiform, insula, caudate, intemal capsule) and pecentral-postcentral gyrus, premotor cortex, supplementary motor area, posterior limb of internal capsule, and thalamus were compared. Conclusions: We did not find any middle cerebral artery territory associated with post-stroke

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30210 - Clinical neurology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    OURNAL OF STROKE & CEREBROVASCULAR DISEASES

  • ISSN

    1052-3057

  • e-ISSN

    1532-8511

  • Volume of the periodical

    27

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    5

  • Pages from-to

    240-245

  • UT code for WoS article

    000419584400033

  • EID of the result in the Scopus database