Elevated jugular venous oxygen saturation after cardiac arrest
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F21%3AA2202CQX" target="_blank" >RIV/61988987:17110/21:A2202CQX - isvavai.cz</a>
Alternative codes found
RIV/00843989:_____/21:E0109261
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S030095722100407X?pes=vor" target="_blank" >https://www.sciencedirect.com/science/article/pii/S030095722100407X?pes=vor</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.resuscitation.2021.10.011" target="_blank" >10.1016/j.resuscitation.2021.10.011</a>
Alternative languages
Result language
angličtina
Original language name
Elevated jugular venous oxygen saturation after cardiac arrest
Original language description
Background: We performed a retrospective analysis of our earlier study on cerebral oxygenation monitoring by jugular venous oximetry (SjvO2) in patients of out-of-hospital cardiac arrest (OHCA). The study was focused on high SjvO2 values (≥75%) and their association with neurological outcomes and serum neuron-specific enolase (NSE) concentration. Method: Forty OHCA patients were divided into (i) high (Group I), (ii) normal (Group II), and (iii) low (Group III) SjvO2, with the mean SjvO2 ≥ 75%, 55–74% and <55% respectively. The neurological outcome was evaluated using the Cerebral Performance Category scale (CPC) on the 90th day after cardiac arrest (post-CA). NSE concentration was determined after ICU admission and then at 24, 48, and 72 hours (h) post-CA. Results: High mean SjvO2 occurred in 67% of patients, while no patients had low mean SjvO2. The unfavourable outcome was significantly more common in Group I than Group II (74% versus 23%, p < 0.01). Group I patients had significantly higher median NSE than Group II at 48 and 72 h post-CA. A positive correlation was found between SjvO2 and PaCO2. Each 1 kPa increase in CO2 led to an increase of SjvO2 by 2.2 %+/-0.66 (p < 0.01) in group I and by 5.7%+/-1.36 (p < 0.0001) in group II. There was no correlation between SjvO2 and MAP or SjvO2 and PaO2. Conclusion: High mean SjvO2 are often associated with unfavourable outcomes and high NSE at 48 and 72 hours post-CA. Not only low but also high SjvO2 values may require therapeutic intervention.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30105 - Physiology (including cytology)
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Resuscitation
ISSN
0300-9572
e-ISSN
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Volume of the periodical
169
Issue of the periodical within the volume
x
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
214-219
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85119209257