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Stroke 20 20: Implementation goals for intravenous thrombolysis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F21%3AA2202DCL" target="_blank" >RIV/61988987:17110/21:A2202DCL - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11150/21:10426606 RIV/00669806:_____/21:10426606 RIV/00159816:_____/21:00074418 RIV/00216208:11120/21:43921787 and 8 more

  • Result on the web

    <a href="https://journals.sagepub.com/doi/pdf/10.1177/23969873211007684" target="_blank" >https://journals.sagepub.com/doi/pdf/10.1177/23969873211007684</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1177/23969873211007684" target="_blank" >10.1177/23969873211007684</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Stroke 20 20: Implementation goals for intravenous thrombolysis

  • Original language description

    Introduction: Knowledge of the implementation gap would facilitate the use of intravenous thrombolysis in stroke, which is still low in many countries. The study was conducted to identify national implementation targets for the utilisation and logistics of intravenous thrombolysis. Material and Method: Multicomponent interventions by stakeholders in health care to optimise prehospital and hospital management with the goal of fast and accessible intravenous thrombolysis for every candidate. Implementation results were documented from prospectively collected cases in all 45 stroke centres nationally. The thrombolytic rate was calculated from the total number of all ischemic strokes in the population of the Czech Republic since 2004. Results: Thrombolytic rates of 1.3 (95%CI 1.1 to 1.4), 5.4 (95%CI 5.1 to 5.7), 13.6 (95%CI 13.1 to 14.0), 23.3 (95%CI 22.8 to 23.9), and 23.5% (95%CI 23.0 to 24.1%) were achieved in 2005, 2009, 2014, 2017, and 2018, respectively. National median door-to-needle times were 60–70 minutes before 2012 and then decreased progressively every year to 25 minutes (IQR 17 to 36) in 2018. In 2018, 33% of both university and non-university hospitals achieved median door-to-needle time ≤20 minutes. In 2018, door-to-needle times ≤20, ≤45, and ≤60 minutes were achieved in 39, 85, and 93% of patients. Discussion: Thrombolysis can be provided to ≥ 20% of all ischemic strokes nationwide and it is realistic to achieve median door-to-needle time 20 minutes. Conclusion: Stroke 20–20 could serve as national implementation target for intravenous thrombolysis and country specific implementation policies should be applied to achieve such target. © European Stroke Organisation 2021.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database

  • CEP classification

  • OECD FORD branch

    30103 - Neurosciences (including psychophysiology)

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    European Stroke Journal

  • ISSN

    2396-9873

  • e-ISSN

  • Volume of the periodical

    6

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    151-159

  • UT code for WoS article

  • EID of the result in the Scopus database

    2-s2.0-85104348392