The relation between clinical phenotypes, gold groups/stages and mortality in copd patients – a prospective multicenter study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F21%3AA2202DF0" target="_blank" >RIV/61988987:17110/21:A2202DF0 - isvavai.cz</a>

Alternative codes found

RIV/00843989:_____/21:E0108978

Result on the web

<a href="https://www.dovepress.com/getfile.php?fileID=68876" target="_blank" >https://www.dovepress.com/getfile.php?fileID=68876</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/COPD.S297087" target="_blank" >10.2147/COPD.S297087</a>

Result language

angličtina

Original language name

The relation between clinical phenotypes, gold groups/stages and mortality in copd patients – a prospective multicenter study

Original language description

Introduction: The concept of phenotyping emerged, reflecting specific clinical, pulmonary and extrapulmonary features of each particular chronic obstructive pulmonary disease (COPD) case. Our aim was to analyze prognostic utility of: “Czech“ COPD phenotypes and their most frequent combinations, ”Spanish” phenotypes and Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages + groups in relation to long-term mortality risk. Methods: Data were extracted from the Czech Multicenter Research Database (CMRD) of COPD. Kaplan-Meier (KM) estimates (at 60 months from inclusion) were used for mortality assessment. Survival rates were calculated for the six elementary “Czech” phenotypes and their most frequent and relevant combinations, “Spanish” phenotypes, GOLD grades and groups. Statistically significant differences were tested by Log Rank test. An analysis of factors underlying mortality risk (the role of confounders) has been assessed with the use of classification and regression tree (CART) analysis. Basic factors showing significant differences between deceased and living patients were entered into the CART model. This showed six different risk groups, the differences in risk were tested by a Log Rank test. Results: The cohort (n=720) was 73.1% men, with a mean age of 66.6 years and mean FEV1 44.4% pred.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

—

OECD FORD branch

30218 - General and internal medicine

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of COPD

ISSN

1176-9106

e-ISSN

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Volume of the periodical

16

Issue of the periodical within the volume

2021

Country of publishing house

NZ - NEW ZEALAND

Number of pages

11

Pages from-to

1171-1182

UT code for WoS article

—

EID of the result in the Scopus database

2-s2.0-85105466703