Causes of Exocrine Pancreatic Insufficiency Other Than Chronic Pancreatitis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F21%3AA2202DJV" target="_blank" >RIV/61988987:17110/21:A2202DJV - isvavai.cz</a>

Alternative codes found

RIV/00843989:_____/21:E0109292 RIV/65269705:_____/21:00074852 RIV/00209805:_____/21:00078966 RIV/00216224:14110/21:00123325

Result on the web

<a href="https://www.webofscience.com/wos/woscc/full-record/WOS:000737842000001" target="_blank" >https://www.webofscience.com/wos/woscc/full-record/WOS:000737842000001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/jcm10245779" target="_blank" >10.3390/jcm10245779</a>

Result language

angličtina

Original language name

Causes of Exocrine Pancreatic Insufficiency Other Than Chronic Pancreatitis

Original language description

Exocrine pancreatic insufficiency (EPI), an important cause of maldigestion and malnutrition, results from primary pancreatic disease or is secondary to impaired exocrine pancreatic function. Although chronic pancreatitis is the most common cause of EPI, several additional causes exist. These include pancreatic tumors, pancreatic resection procedures, and cystic fibrosis. Other diseases and conditions, such as diabetes mellitus, celiac disease, inflammatory bowel disease, and advanced patient age, have also been shown to be associated with EPI, but the exact etiology of EPI has not been clearly elucidated in these cases. The causes of EPI can be divided into loss of pancreatic parenchyma, inhibition or inactivation of pancreatic secretion, and postcibal pancreatic asynchrony. Pancreatic enzyme replacement therapy (PERT) is indicated for the conditions described above presenting with clinically clear steatorrhea, weight loss, or symptoms related to maldigestion and malabsorption. This review summarizes the current literature concerning those etiologies of EPI less common than chronic pancreatitis, the pathophysiology of the mechanisms of EPI associated with each diagnosis, and treatment recommendations.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30218 - General and internal medicine

Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Clinical Medicine

ISSN

2077-0383

e-ISSN

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Volume of the periodical

10

Issue of the periodical within the volume

24

Country of publishing house

CH - SWITZERLAND

Number of pages

22

Pages from-to

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UT code for WoS article

000737842000001

EID of the result in the Scopus database

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