Comparison of carotid endarterectomy and repeated carotid angioplasty and stenting for in-stent restenosis (CERCAS trial): a randomised study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F23%3AA2402L0J" target="_blank" >RIV/61988987:17110/23:A2402L0J - isvavai.cz</a>

Alternative codes found

RIV/61383082:_____/23:00001311

Result on the web

<a href="https://www.webofscience.com/wos/woscc/full-record/WOS:000969265700001" target="_blank" >https://www.webofscience.com/wos/woscc/full-record/WOS:000969265700001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1136/svn-2022-002075" target="_blank" >10.1136/svn-2022-002075</a>

Result language

angličtina

Original language name

Comparison of carotid endarterectomy and repeated carotid angioplasty and stenting for in-stent restenosis (CERCAS trial): a randomised study

Original language description

Background and aim In-stent restenosis (ISR) belongs to an infrequent but potentially serious complication after carotid angioplasty and stenting in patients with severe carotid stenosis. Some of these patients might be contraindicated to repeat percutaneous transluminal angioplasty with or without stenting (rePTA/S). The purpose of the study is to compare the safety and effectiveness of carotid endarterectomy with stent removal (CEASR) and rePTA/S in patients with carotid ISR. Methods Consecutive patients with carotid ISR (>= 80%) were randomly allocated to the CEASR or rePTA/S group. The incidence of restenosis after intervention, stroke, transient ischaemic attack myocardial infarction and death 30 days and 1 year after intervention and restenosis 1 year after intervention between patients in CEASR and rePTA/S groups were statistically evaluated. Results A total of 31 patients were included in the study; 14 patients (9 males; mean age 66.3 +/- 6.6 years) were allocated to CEASR and 17 patients (10 males; mean age 68.8 +/- 5.6 years) to the rePTA/S group. The implanted stent in carotid restenosis was successfully removed in all patients in the CEASR group. No clinical vascular event was recorded periproceduraly, 30 days and 1 year after intervention in both groups. Only one patient in the CEASR group had asymptomatic occlusion of the intervened carotid artery within 30 days and one patient died in the rePTA/S group within 1 year after intervention. Restenosis after intervention was significantly greater in the rePTA/S group (mean 20.9%) than in the CEASR group (mean 0%, p=0.04), but all stenoses were <50%. Incidence of 1-year restenosis that was =70% did not differ between the rePTA/S and CEASR groups (4 vs 1 patient; p=0.233). Conclusion CEASR seems to be effective and save procedures for patients with carotid ISR and might be considered as a treatment option.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30210 - Clinical neurology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

STROKE AND VASCULAR NEUROLOGY

ISSN

2059-8688

e-ISSN

2059-8696

Volume of the periodical

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Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

399-404

UT code for WoS article

000969265700001

EID of the result in the Scopus database

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