The importance of multimodal CT examination in stroke mimics diagnosis: design of prospective observational multicentre study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F24%3AA2503AJU" target="_blank" >RIV/61988987:17110/24:A2503AJU - isvavai.cz</a>

Alternative codes found

RIV/00843989:_____/24:E0110999 RIV/00159816:_____/24:00081489 RIV/00216224:90034/24:00136542 RIV/61989100:27240/24:10256965

Result on the web

<a href="https://www.frontiersin.org/articles/10.3389/fneur.2024.1365986/full" target="_blank" >https://www.frontiersin.org/articles/10.3389/fneur.2024.1365986/full</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fneur.2024.1365986" target="_blank" >10.3389/fneur.2024.1365986</a>

Result language

angličtina

Original language name

The importance of multimodal CT examination in stroke mimics diagnosis: design of prospective observational multicentre study

Original language description

Introduction: Non-contrast computed tomography (CT) and CT angiography are the gold standard in neuroimaging diagnostics in the case of suspected stroke. CT perfusion (CTP) may play an important role in the diagnosis of stroke mimics (SM), but currently, it is not a standard part of the stroke diagnostic procedure. The project is a multicentre prospective observational clinical research focused on refining the diagnostics of stroke and stroke mimics (SM) in hospital care. Aim: This study aimed to evaluate the degree of specificity and sensitivity of multimodal CT (NCCT, CTA, and CTP) in the diagnosis of SM versus stroke. Methodology: In this study, we will include 3,000 patients consecutively admitted to the comprehensive stroke centres with a diagnosis of suspected stroke. On the basis of clinical parameters and the results of multimodal CT and magnetic resonance imaging (MRI), the diagnosis of stroke and SM will be established. To clarify the significance of the use of the multimodal CT scan, the analysis will include a comparison of the blinded results for each imaging scan performed by radiologists and AI technology and a comparison of the initial and final diagnosis of the enrolled patients. Based on our results, we will compare the economic indicators and costs that would be saved by not providing inadequate treatment to patients with SM. Conclusion: The expected outcome is to present an optimised diagnostic procedure that results in a faster and more accurate diagnosis, thereby eliminating the risk of inadequate treatment in patients with SM. Clinical trial registration: clinicaltrials.gov, NCT06045455.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30210 - Clinical neurology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

FRONTIERS IN NEUROLOGY

ISSN

1664-2295

e-ISSN

1664-2295

Volume of the periodical

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Issue of the periodical within the volume

04 June 2024

Country of publishing house

CH - SWITZERLAND

Number of pages

7

Pages from-to

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UT code for WoS article

001249589200001

EID of the result in the Scopus database

2-s2.0-85196274609