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Evolution of metabolic capabilities and molecular features of diplonemids, kinetoplastids, and euglenids

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F20%3AA21025D5" target="_blank" >RIV/61988987:17310/20:A21025D5 - isvavai.cz</a>

  • Alternative codes found

    RIV/60077344:_____/20:00537292 RIV/60076658:12310/20:43901110 RIV/00216208:11310/20:10411521

  • Result on the web

    <a href="https://bmcbiol.biomedcentral.com/track/pdf/10.1186/s12915-020-0754-1" target="_blank" >https://bmcbiol.biomedcentral.com/track/pdf/10.1186/s12915-020-0754-1</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1186/s12915-020-0754-1" target="_blank" >10.1186/s12915-020-0754-1</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Evolution of metabolic capabilities and molecular features of diplonemids, kinetoplastids, and euglenids

  • Original language description

    Background The Euglenozoa are a protist group with an especially rich history of evolutionary diversity. They include diplonemids, representing arguably the most species-rich clade of marine planktonic eukaryotes; trypanosomatids, which are notorious parasites of medical and veterinary importance; and free-living euglenids. These different lifestyles, and particularly the transition from free-living to parasitic, likely require different metabolic capabilities. We carried out a comparative genomic analysis across euglenozoan diversity to see how changing repertoires of enzymes and structural features correspond to major changes in lifestyles. Results We find a gradual loss of genes encoding enzymes in the evolution of kinetoplastids, rather than a sudden decrease in metabolic capabilities corresponding to the origin of parasitism, while diplonemids and euglenids maintain more metabolic versatility. Distinctive characteristics of molecular machines such as kinetochores and the pre-replication complex that were previously considered specific to parasitic kinetoplastids were also identified in their free-living relatives. Therefore, we argue that they represent an ancestral rather than a derived state, as thought until the present.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    BMC BIOLOGY

  • ISSN

    1741-7007

  • e-ISSN

  • Volume of the periodical

    18

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    28

  • Pages from-to

    23

  • UT code for WoS article

    000519976800001

  • EID of the result in the Scopus database