Genomics of New Ciliate Lineages Provides Insight into the Evolution of Obligate Anaerobiosis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F20%3AA21025E1" target="_blank" >RIV/61988987:17310/20:A21025E1 - isvavai.cz</a>

Alternative codes found

RIV/60077344:_____/20:00540095 RIV/00216208:11310/20:10414664 RIV/60076658:12310/20:43901424

Result on the web

<a href="https://www.sciencedirect.com/science/article/abs/pii/S0960982220304346" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0960982220304346</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.cub.2020.03.064" target="_blank" >10.1016/j.cub.2020.03.064</a>

Result language

angličtina

Original language name

Genomics of New Ciliate Lineages Provides Insight into the Evolution of Obligate Anaerobiosis

Original language description

Oxygen plays a crucial role in energetic metabolism of most eukaryotes. Yet adaptations to low-oxygen concentrations leading to anaerobiosis have independently arisen in many eukaryotic lineages, resulting in a broad spectrum of reduced and modified mitochondrion-related organelles (MROs). In this study, we present the discovery of two new class-level lineages of free-living marine anaerobic ciliates, Muranotrichea, cl. nov. and Parablepharismea, cl. nov., that, together with the class Armophorea, form a major clade of obligate anaerobes (APM ciliates) within the Spirotrichea, Armophorea, and Litostomatea (SAL) group. To deepen our understanding of the evolution of anaerobiosis in ciliates, we predicted the mitochondrial metabolism of cultured representatives from all three classes in the APM clade by using transcriptomic and metagenomic data and performed phylogenomic analyses to assess their evolutionary relationships. The predicted mitochondrial metabolism of representatives from the APM ciliates reveals functional adaptations of metabolic pathways that were present in their last common ancestor and likely led to the successful colonization and diversification of the group in various anoxic environments. Furthermore, we discuss the possible relationship of Parablepharismea to the uncultured deep-sea class Cariacotrichea on the basis of single-gene analyses. Like most anaerobic ciliates, all studied species of the APM clade host symbionts, which we propose to be a significant accelerating factor in the transitions to an obligately anaerobic lifestyle. Our results provide an insight into the evolutionary mechanisms of early transitions to anaerobiosis and shed light on fine-scale adaptations in MROs over a relatively short evolutionary time frame.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

CURR BIOL

ISSN

0960-9822

e-ISSN

1879-0445

Volume of the periodical

30

Issue of the periodical within the volume

11

Country of publishing house

US - UNITED STATES

Number of pages

13

Pages from-to

2037-2050

UT code for WoS article

000538803300025

EID of the result in the Scopus database

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