Amino Acid Composition in Various Types of Nucleic Acid-Binding Proteins

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F21%3AA22029NS" target="_blank" >RIV/61988987:17310/21:A22029NS - isvavai.cz</a>
Result on the web
<a href="https://www.mdpi.com/1422-0067/22/2/922" target="_blank" >https://www.mdpi.com/1422-0067/22/2/922</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms22020922" target="_blank" >10.3390/ijms22020922</a>

Result language
angličtina
Original language name
Amino Acid Composition in Various Types of Nucleic Acid-Binding Proteins
Original language description
Nucleic acid-binding proteins are traditionally divided into two categories: With the ability to bind DNA or RNA. In the light of new knowledge, such categorizing should be overcome because a large proportion of proteins can bind both DNA and RNA. Another even more important features of nucleic acid-binding proteins are so-called sequence or structure specificities. Proteins able to bind nucleic acids in a sequence-specific manner usually contain one or more of the well-defined structural motifs (zinc-fingers, leucine zipper, helix-turn-helix, or helix-loop-helix). In contrast, many proteins do not recognize nucleic acid sequence but rather local DNA or RNA structures (G-quadruplexes, i-motifs, triplexes, cruciforms, left-handed DNA/RNA form, and others). Finally, there are also proteins recognizing both sequence and local structural properties of nucleic acids (e.g., famous tumor suppressor p53). In this mini-review, we aim to summarize current knowledge about the amino acid composition of various types of nucleic acid-binding proteins with a special focus on significant enrichment and/or depletion in each category.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10601 - Cell biology

Project
<a href="/en/project/QK1810391" target="_blank" >QK1810391: Utilization of genomic and transcriptomic approaches to create genetic resources and breeding materials of poppy with specific traits</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)