High genetic diversity of immunity genes in an expanding population of a highly mobile carnivore, the grey wolf Canis lupus, in Central Europe
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F21%3AA2202EAS" target="_blank" >RIV/61988987:17310/21:A2202EAS - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/21:10439453
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ddi.13360" target="_blank" >https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ddi.13360</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/ddi.13360" target="_blank" >10.1111/ddi.13360</a>
Alternative languages
Result language
angličtina
Original language name
High genetic diversity of immunity genes in an expanding population of a highly mobile carnivore, the grey wolf Canis lupus, in Central Europe
Original language description
Aim: The aim of the study was to assess the effect of changes in population size and migration on variation in functional immunity genes in the previously bottlenecked population of the grey wolf, Canis lupus. Location: Eastern/Central Europe: Poland, Czechia, Slovakia. Methods: We genotyped 7 immunity genes: three MHC-DLA genes (dog leuko- cyte antigen) and four Toll-like receptor (TLR) genes among 130 wolves originating from three populations: two lowland (Baltic and Central European), and highland Carpathian. We contrasted the population structure in immunity genes with a neu- tral structure based on 13 microsatellites, and we analysed signatures of selection in the immunity loci. Results: We found high overall genetic variance in immunity genes and no evidence for decreased diversity in the recently established populations. The population struc- ture in immunity loci was weak, with pairwise F ST lower than for neutral markers. Although the results of neutrality tests were not significant, we identified codons under selection, both positive and negative. Main Conclusions: We demonstrated that despite recent population expansion which is expected to result in decreased genetic diversity, the diversity of immunity genes in the newly established wolf population is similar to those in the source population. This suggests that migrations do not cause allele loss in grey wolf. Signatures of selec- tion on codon level, but not in tests using allele frequencies, suggest the contrasting effects of demography and selection.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10613 - Zoology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
DIVERS DISTRIB
ISSN
1366-9516
e-ISSN
1472-4642
Volume of the periodical
27
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
16
Pages from-to
1680-1695
UT code for WoS article
000662972700001
EID of the result in the Scopus database
2-s2.0-85107953898