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Determining optical mapping errors by simulations

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27240%2F21%3A10248027" target="_blank" >RIV/61989100:27240/21:10248027 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15110/21:73609650 RIV/00098892:_____/21:N0000071

  • Result on the web

    <a href="https://academic.oup.com/bioinformatics/article-abstract/37/20/3391/6275255?redirectedFrom=fulltext" target="_blank" >https://academic.oup.com/bioinformatics/article-abstract/37/20/3391/6275255?redirectedFrom=fulltext</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1093/bioinformatics/btab259" target="_blank" >10.1093/bioinformatics/btab259</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Determining optical mapping errors by simulations

  • Original language description

    Optical mapping is a complementary technology to traditional DNA sequencing technologies, such as next-generation sequencing (NGS). It provides genome-wide, high-resolution restriction maps from single, stained molecules of DNA. It can be used to detect large and small structural variants, copy number variations and complex rearrangements. Optical mapping is affected by different kinds of errors in comparison with traditional DNA sequencing technologies. It is important to understand the source of these errors and how they affect the obtained data. This article proposes a novel approach to modeling errors in the data obtained from the Bionano Genomics Inc. Saphyr system with Direct Label and Stain (DLS) chemistry. Some studies have already addressed this issue for older instruments with nicking enzymes, but we are unaware of a study that addresses this new system.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10200 - Computer and information sciences

Result continuities

  • Project

    <a href="/en/project/NU20-06-00269" target="_blank" >NU20-06-00269: Utility of cellular profiles and proteomics of synovial fluid and periprosthetic tissues for clinical decision making in knee osteoarthritis</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Bioinformatics

  • ISSN

    1367-4803

  • e-ISSN

  • Volume of the periodical

    37

  • Issue of the periodical within the volume

    20

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    7

  • Pages from-to

    3391-3397

  • UT code for WoS article

    000733829400001

  • EID of the result in the Scopus database