Modeling a neurological disorder as the result of an operator acting on the brain: A first sketch based on network channel modeling

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27240%2F24%3A10257613" target="_blank" >RIV/61989100:27240/24:10257613 - isvavai.cz</a>

Result on the web

<a href="https://pubs.aip.org/aip/cha/article-abstract/34/5/053133/3294604/Modeling-a-neurological-disorder-as-the-result-of?redirectedFrom=fulltext" target="_blank" >https://pubs.aip.org/aip/cha/article-abstract/34/5/053133/3294604/Modeling-a-neurological-disorder-as-the-result-of?redirectedFrom=fulltext</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1063/5.0199988" target="_blank" >10.1063/5.0199988</a>

Result language

angličtina

Original language name

Modeling a neurological disorder as the result of an operator acting on the brain: A first sketch based on network channel modeling

Original language description

The brain is a complex network, and diseases can alter its structures and connections between regions. Therefore, we can try to formalize the action of diseases by using operators acting on the brain network. Here, we propose a conceptual model of the brain, seen as a multilayer network, whose intra-lobe interactions are formalized as the diagonal blocks of an adjacency matrix. We propose a general and abstract definition of disease as an operator altering the weights of the connections between neural agglomerates, that is, the elements of the brain matrix. As models, we consider examples from three neurological disorders: epilepsy, Alzheimer-Perusini&apos;s disease, and schizophrenia. The alteration of neural connections can be seen as alterations of communication pathways, and thus, they can be described with a new channel model.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10102 - Applied mathematics

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chaos

ISSN

1054-1500

e-ISSN

1089-7682

Volume of the periodical

34

Issue of the periodical within the volume

5

Country of publishing house

US - UNITED STATES

Number of pages

15

Pages from-to

nestránkováno

UT code for WoS article

001231939100001

EID of the result in the Scopus database

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