Microwave-assisted synthesis and characterization of antibacterial O-crosslinked chitosan hydrogels doped with TiO2 nanoparticles for skin regeneration
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27350%2F19%3A10240382" target="_blank" >RIV/61989100:27350/19:10240382 - isvavai.cz</a>
Result on the web
<a href="https://www.tandfonline.com/doi/abs/10.1080/00914037.2018.1517351" target="_blank" >https://www.tandfonline.com/doi/abs/10.1080/00914037.2018.1517351</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/00914037.2018.1517351" target="_blank" >10.1080/00914037.2018.1517351</a>
Alternative languages
Result language
angličtina
Original language name
Microwave-assisted synthesis and characterization of antibacterial O-crosslinked chitosan hydrogels doped with TiO2 nanoparticles for skin regeneration
Original language description
Tissue engineering provides alternative solutions to traditional transplantation. In this study a novel strategy of chitosan scaffolds obtainment based on selective O-crosslinking using Aspartic acid and the addition of TiO2 nanoparticles is presented. Prepared under microwave conditions biomaterials were of increased mechanical and thermal durability thanks to NPs presence comparing to pure chitosan. Moreover porous scaffolds maintained antimicrobial activity against S. Aureus and E. Coli. Biomaterials were susceptible to in vitro biodegradation and degradation. Hydrogels exhibited positive impact on proliferation activity of fibroblasts. Thus they may be applied as 3D scaffolds in tissue engineering focused on wound healing. (C) 2018, (C) 2018 Taylor & Francis.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Polymeric Materials and Polymeric Biomaterials
ISSN
0091-4037
e-ISSN
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Volume of the periodical
68
Issue of the periodical within the volume
15
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
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UT code for WoS article
000472755300001
EID of the result in the Scopus database
2-s2.0-85054846052