Grain Size and Electrochemical Surface Modification Effects on Corrosion, Biological, and Technological Properties of CP Titanium Implants

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27350%2F25%3A10259679" target="_blank" >RIV/61989100:27350/25:10259679 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11140/25:10507395 RIV/61989100:27360/25:10259679 RIV/61989100:27730/25:10259679

Result on the web

<a href="https://www.mdpi.com/2079-4983/16/12/439" target="_blank" >https://www.mdpi.com/2079-4983/16/12/439</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/jfb16120439" target="_blank" >10.3390/jfb16120439</a>

Result language

angličtina

Original language name

Grain Size and Electrochemical Surface Modification Effects on Corrosion, Biological, and Technological Properties of CP Titanium Implants

Original language description

Commercially pure (CP) titanium is widely used for long-term biomedical implants due to its high biocompatibility and corrosion resistance. However, its relatively low strength limits its use in highly loaded applications. Ultrafine-grained (UFG) titanium obtained through severe plastic deformation offers enhanced mechanical performance while maintaining the stability of CP titanium. This study investigates how electrochemical surface modification by anodization affects the corrosion, biological performance, and technological behavior of UFG titanium. TiO2 layers with nanotubular and nanoporous morphologies were produced at anodization voltages between 20 and 60 V. Corrosion tests in physiological solution confirmed stable passive behavior with corrosion rates below 4 mu m year-1, and surface wettability increased markedly with anodization. Osteoblast-like MG-63 cells exhibited good viability on all anodized surfaces, with improved adhesion and proliferation on samples anodized at 60 V. The porous TiO2 layers were successfully intercalated with dimethyl sulfoxide and ibuprofen, demonstrating potential for local drug delivery. Implantation simulations on real Nanoimplant (R) prototypes confirmed sufficient mechanical stability of the anodized layer. Overall, the optimized anodization of UFG titanium enhances its biological response while maintaining corrosion resistance, supporting its clinical use in long-term dental and orthopedic implants with integrated drug-release functionality.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

20501 - Materials engineering

Project

<a href="/en/project/EH22_008%2F0004631" target="_blank" >EH22_008/0004631: Materials and technologies for sustainable development</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Functional Biomaterials

ISSN

2079-4983

e-ISSN

2079-4983

Volume of the periodical

16

Issue of the periodical within the volume

12

Country of publishing house

CH - SWITZERLAND

Number of pages

26

Pages from-to

nestránkováno

UT code for WoS article

001646818800001

EID of the result in the Scopus database

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