Natural versus organophilized smectites as drug adsorbents: experiment and molecular modeling

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27360%2F25%3A10258408" target="_blank" >RIV/61989100:27360/25:10258408 - isvavai.cz</a>

Alternative codes found

RIV/61989100:27640/25:10258408

Result on the web

<a href="https://pubs.rsc.org/en/content/articlelanding/2025/ra/d5ra04769b" target="_blank" >https://pubs.rsc.org/en/content/articlelanding/2025/ra/d5ra04769b</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/D5RA04769B" target="_blank" >10.1039/D5RA04769B</a>

Result language

angličtina

Original language name

Natural versus organophilized smectites as drug adsorbents: experiment and molecular modeling

Original language description

To adsorb pollutants from water, smectites are commonly modified with quaternary ammonium compounds. However, these are also environmentally hazardous. This study aims to highlight that original smectites can compete with modified ones and that modification is not necessary. Original smectites – montmorillonite (MMT), beidellite (BEI), nontronite (NON) – and the same smectites modified with tetradecyltrimethylammonium (TTA+), denoted as MMT-M, BEI-M, NON-M, were studied as adsorbents of drugs ampicillin (AMP) and lamotrigine (LAM). Adsorbents before and after adsorption were studied using Fourier-transform infrared spectroscopy, elemental analysis, X-ray powder diffraction, thermogravimetry, and molecular modeling. Adsorption efficiency of original smectites reaches or exceeds (for LAM on BEI and NON) 50 mg per 1 g of adsorbent. Adsorption is not monolayer and the order BEI &gt; MMT &gt; NON for both AMP and LAM was found. While AMP is preferentially adsorbed through interaction with Na+, LAM is preferentially adsorbed through interactions with other LAMs. For modified smectites, the adsorption efficiency ranges from units to lower tens of mg per 1 g of adsorbent in the order MMT-M &gt; NON-M &gt; BEI-M and NON-M &gt; MMT-M &gt; BEI-M for AMP and LAM, respectively. The adsorption can be considered monolayer, and it is not controlled only by the strength of drug – TTA+ interaction. It can be concluded that (1) the modification did not enhance the adsorption efficiency of original smectites, (2) the original smectites showed higher adsorption efficiency compared to the modified ones, and (3) the original smectites are a suitable environmentally friendly alternative to the commonly used modified smectites.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

20505 - Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics; filled composites)

Project

<a href="/en/project/EH22_008%2F0004631" target="_blank" >EH22_008/0004631: Materials and technologies for sustainable development</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

RSC Advances

ISSN

2046-2069

e-ISSN

2046-2069

Volume of the periodical

15

Issue of the periodical within the volume

43

Country of publishing house

GB - UNITED KINGDOM

Number of pages

19

Pages from-to

36065-36083

UT code for WoS article

001584605900001

EID of the result in the Scopus database

2-s2.0-105017424939